Post National Interest Exemption Approval Travel Experience for Global Entry

Hi:

I need to get back to India for a personal issue and work in a NIE field so pretty confident of getting it. I read all the experiences for folks coming back from India who had secondary screening, wanted to see if Global Entry is still functional or if anyone had that and what was the experience if you tried using it?

Also to confirm, you can only apply for NIE once in India right? Cannot apply from the US?

Thanks,

Kaushal