Does Port of entry matters for F1 visa

My brother is traveling to US on F1 visa.
He got admission in North West Missouri State University at Maryville,Missouri and the nearst international airport there is Kansas City.
He is planning to meet me in NY and stay here for couple of days before reporting to college,
Will this be a issue at immigation check point as port of entry will be NYC not Kansas city
and he will be staying in NYC for few days before going to his college.

That’s not at all an issue. U can say that U met a friend/relative

Not an issue. Make sure you have him fill Maryville, Missouri address in the US visitor control form given on the aircraft. He will be questioned if a New York address is written with a direct mismatch to the Missouri I-20, it is anyway just a 2-3 day stay.

All the best

Dr. Sandeep Shankar, Colorado Heights University, Denver, CO 80223, USA.; Email: