Travel during H1B registration

I wanted to know, as this year the registration for lottery will start in March and the result will come approximately in the last week of that month. Wanted to know can I travel outside United States in March? and in any way will it affect the application if selected in lottery?

No, it should NOT impact your Lottery chances, if you travel. If you are filing as COS, you need to be back before they file petition. Talk to your employer on this and plan accordingly. You can check out