H4 Visa Currently with a approved H1B for this year 2014


My wife is in H4 visa now and she got her H1B visa approved somedays back. Now she wants to travel to India and return back in the month of september in H4 itself. Will this affect the approved H1b petition anyways?

The I-94 number what we gave for the approved H1B petition may get changed once she returns back again in H4. Please let me know whether she can come back and start working on H1B from Oct-1 without any issues.