Can we file second h1b amendment when first amendment is still pending?

We filed h1b amendment 2 months ago when I joined new client new location. It was filed in normal and is still pending and in progress. Not yet approved…

Now my question is I want to change to new client and new location so Can we file second amendment now? Does it matter if first amendment is denied or approved later on?

I mean suppose first amendment is still pending,and then we file second amendment and start working for new client at new location after getting receipt…So now both first and second amendments are pending…

So how does it work… Do I need just second amendment approval now or first amendment still has any role to play?

Or Only second amendment approval decision will matter now?

Another amendment can be applied while the 1st one is pending.